Posted: Wed., Jul. 22, 2009, 6:06pm PT

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John Stamos

John Stamos ("ER") has been cast in the indie comedy "Father of Invention" starring Kevin Spacey. Stamos will play the man who has taken over Spacey’s business and eventually steals his big comeback idea.

Virginia Madsen and Heather Graham also star in the film, which has begun filming in New Orleans.

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